The American Cancer Society (ACS) has released the latest guidelines for cervical cancer screening, which is updated on the basis of the 2020 version, combined with the latest medical research and testing technology progress, and clarifies the key contents such as cervical cancer screening plans, testing method selection and screening cycles for different populations, providing a new clinical reference for early screening and prevention and control of cervical cancer. Regular screening for precancerous lesions can significantly reduce the risk of cervical cancer. This guideline is mainly applicable to the average risk group of cervical cancer, and also makes a supplementary explanation of the screening plan for high-risk groups, clarifying the starting and ending age of screening and the application specifications of various testing methods.